What is 2-Bromo-4-methylpropiophenone cas 1451-82-7?

2-Bromo-4-methylpropiophenone Basic information

2-Bromo-4′-methylpropiophenone is an organic compound with the chemical formula C 10 H 11 BrO. White crystal powder. The chemical’s systematic name is 2-bromo-1-(4-methylphenyl)propan-1-one. CAS registration number 1451-82-7, also known as 1-Propanone,BK4, bromketon-4,2-bromo-1-(4-methylryl)-. The molecular weight is 227.10.

2-Bromo-4-methylpropiophenone uses

2-Bromo-4′-methylpropiophenone is a phenolic compound. It is used as a solvent for silicone rubber and as a colorant in plastics, paints and enamels. 2-Bromo-4′-methylpropiophenone has been shown to be an effective antioxidant in ceramics, silicone and silicone rubber.

2-Bromo-4-methylpropiophenone wiki

It was first synthesized by Alexander Shulkin. In his book “PiHKAL”, the dose is listed as 350 mg for an unknown duration.

Synthesis of 2-bromo-4-methylpropiophenone

14.8 g (0.1 mol) of 4′-methylpropiophenone were added to 100 ml of chloroform, and a small amount of finely ground aluminum chloride and 15.9 g (0.1 mol; 5 ml) of bromine in 20 water were added. Add 1 ml of chloroform dropwise while cooling in an ice bath. The mixture was allowed to react at ambient temperature overnight. It is then filtered, the solvent is evaporated from the filtrate and the crystallized residue is washed with diethyl ether. 21.5g of crystals were collected.

2-Bromo-4-methylpropiophenone Cas 1451-82-7

Usually used as intermediates and raw materials in fine chemical industry. Specifically. Furthermore, this compound can be used as an active ingredient for preparing therapeutically useful 1-phenyl-2-piperidylalkanol derivatives. Furthermore, this substance has been shown to be involved in the preparation of pharmaceutical compositions containing azole derivatives, which show desirable activity in the treatment of frequent urination or urinary incontinence.

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