Ethylmagnesium bromide CAS 925-90-6

Ethylmagnesium bromide CAS 925-90-6 Product details

Ethylmagnesium bromide is generally sold as a dark brown solution and can be dissolved in diethyl ether, butyl ether, isopropyl ether, THF and anisole.

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Ethylmagnesium bromide CAS 925-90-6 Product Picture

Ethylmagnesium bromide CAS 925-90-6 Application/Use

Ethylmagnesium bromide, also known as ethylmagnesiumbromide or Grignard reagent, is an organometallic compound with the chemical formula C2H5MgBr. It is a highly reactive and versatile reagent commonly used in organic synthesis.

The primary application of ethylmagnesium bromide is as a nucleophile in organic reactions. It is widely employed in the Grignard reaction, which involves the addition of the ethylmagnesium bromide to various electrophiles such as carbonyl compounds (aldehydes, ketones, esters) or epoxides. This reaction forms carbon-carbon bonds, allowing for the synthesis of a broad range of organic compounds.

Some specific applications of ethylmagnesium bromide include:

Alcohol synthesis: Ethylmagnesium bromide can be reacted with aldehydes or ketones to produce alcohols. This reaction is often used to extend carbon chains or introduce functional groups into organic molecules.
Carboxylic acid synthesis: Ethylmagnesium bromide can react with carbon dioxide to form carboxylic acids. This reaction, known as the Grignard carboxylation, is an important method for the preparation of carboxylic acids.
Reduction reactions: Ethylmagnesium bromide can reduce various functional groups, including carbonyl compounds, nitriles, and halides, to yield the corresponding alcohols, amines, or hydrocarbons.
Coupling reactions: Ethylmagnesium bromide can be used in cross-coupling reactions to form carbon-carbon bonds. For example, it can react with aryl or vinyl halides in the presence of a palladium catalyst to form biaryl or alkenyl compounds.

Ethylmagnesium bromide CAS 925-90-6 Synonyms/Tags/Keywords

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