CAS 4584-49-0 2-Dimethylaminoisopropyl chloride hydrochloride

  • 2-Dimethylaminoisopropyl chloride hydrochloride,2-DMPC, 4584-49-0,CAS 4584490
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CAS 4584-49-0 2-Dimethylaminoisopropyl chloride hydrochloride Product Details

N,N-dimethylamino-2-chloropropane hydrochloride is a key intermediate in the synthesis of many drugs such as the antipsychotic chlorpromazine and the antidepressant imipramine [1]. It has a chemical formula of C5H13Cl2N and a molecular weight of 158.07. Chemical material. The Chinese aliases are 3-chloro-N,N-dimethylpropylamine hydrochloride, 3-dimethylaminochloropropane hydrochloride, etc. The English name is 2-Dimethylaminoisopropyl chloride hydrochloride, and the compound abbreviation is DMPA. White to light yellow crystalline powder, melting point 187-190 °C (lit.), boiling point 130.7ºC at 760mmHg. The warehouse should be kept at a low temperature, ventilated and dry, and stored separately from food raw materials.

CAS 4584-49-0 2-Dimethylaminoisopropyl chloride hydrochloride Picture

CAS 4584-49-0
CAS 4584-49-0

CAS 4584-49-0 2-Dimethylaminoisopropyl chloride hydrochloride Application/Usage

1) N,N-dimethylamino-2-chloropropane hydrochloride is used to synthesize chlorpromazine, doxepin hydrochloride, Telden and other drugs.

2) Intermediates of the central nervous system depressant drug Mesantong and the antihistamine drug Phenergan.

3) Used as raw materials for organic synthesis to prepare (3(3(dimethylamino)propoxy)phenyl)boric acid and other substances [2]. Using 3-hydroxyphenylboronic acid as the starting material, 3-hydroxyphenylboronic acid pinacol ester is prepared through esterification reaction. Then, 3-hydroxyphenylboronic acid pinacol ester is coupled with N,N-dimethylamino-2-chloropropane hydrochloride to prepare (3(3(dimethylamino)propoxy)phenyl)boronic acid Pinacol ester. Finally, (3(3(dimethylamino)propoxy)phenyl)boronic acid pinacol ester is hydrolyzed to obtain (3(3(dimethylamino)propoxy)phenyl)boronic acid. This method has a short process route, convenient operation, mild and easy-to-control reaction conditions, low cost, easy industrialization, avoids the use of expensive catalysts, and the use of highly dangerous metal bases, is easy to purify, and has a high yield.

CAS 4584-49-0 2-Dimethylaminoisopropyl chloride hydrochloride Synonyms/tags/keywords

N,N-dimethylamino-2-chloropropane hydrochloride,CAS 4584-49-0,2-DMPC, 4584-49-0,CAS 4584490,2-Dimethylaminoisopropyl chloride hydrochloride


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Session: 05df0f7ead19920dce6405322cc46b108c3e287d2a9f91a6e028d1424a2395586d

Product Name

2-Dimethylaminoisopropyl chloride hydrochloride



Molecular Formula



White Powder


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